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Search Results for " angiotensin ii at1-receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T2531 Eprosartan Mesylate SKF-108566J RAAS
Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.
T1461 Candesartan CV 11974 RAAS
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T1615 Irbesartan SR-47436,BMS-186295 Apoptosis , RAAS
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T13390 ZD 7155 hydrochloride RAAS
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
T0215 Losartan potassium DuP-753 potassium,MK 954,DuP 753 RAAS
Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor.
T14337 Buloxibutid AT2 receptor agonist C21 RAAS
Buloxibutid (AT2 receptor agonist C21) is a novel and selective small molecule angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and 10 μM for AT2 and AT1 receptors, respectively.
T2400 Candesartan Cilexetil TCV-116 Apoptosis , RAAS
Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with...
T35834L (Sar¹)-Angiotensin II acetate RAAS
(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell...
TP2158L1 TRV-120027 acetate (1234510-46-3 free base) RAAS , Arrestin
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signaling.
T1518 Olmesartan Medoxomil CS 866,Benicar RAAS
Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
T0215L Losartan DuP-753 RAAS
Losartan (DuP-753) is an angiotensin II receptor antagonist.
T2531L Eprosartan KF-108566J free base,Teveten RAAS
Eprosartan (SKF-108566J free base) is a selective and competitive nonpeptide angiotensin II receptor antagonist with high affinity for AT1 receptor subtypes and can be used as an antihypertensive agent.Eprosartan has an ...
T21591 1H-1-ethyl Candesartan Cilexetil Others
1H-1-ethyl Candesartan Cilexetil is a process-related impurity in the bulk synthesis of candesartan cilexetil, which is a potent, long-acting and selective angiotensin II type 1 receptor (AT1) antagonist.
T19930 Nitrosoglutathione S-Nitrosoglutathione,SNOG,Glutathione thionitrite,GSNO RAAS , NO Synthase
Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, i...
T8560 Angiotensin II human acetate Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate Apoptosis , RAAS
Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.
T2322 Fimasartan BR-A-657,Kanarb Apoptosis , RAAS
Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has show...
T10323 Angiotensin II (3-8), human TFA RAAS
Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
T31845 Forasartan SC52458,SC 52458,SC-52458
Forasartan is a non - peptide angiotensin II receptor antagonist with antihypertensive activity. Forasartan and angiotensin II compete to bind AT1 receptor subtypes in vascular smooth muscle, thereby blocking angiotensin...
T5824 Angiotensin II (3-8), human Angiotensin IV RAAS
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.
T70225 L-159884
L-159884 is a radiolabelled, nonpeptide angiotensin II antagonist that is useful for angiotensin II, AT1 receptor imaging
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